Turning the clock ahead or back one hour during daylight saving time transitions may be tied to an increased risk of ischemic stroke, but only temporarily, according to a preliminary study.
Although asking about maternal depression increased among pediatricians by about 30 percent between 2004 and 2013, less than half of pediatricians usually screen for the condition.
According to researchers, cannabis significantly affects users’ ability to recognize, process and empathize with human emotions like happiness, sadness and anger.
Imagine you wanted to know how much energy it took to bike up a mountain, but couldn’t finish the ride to the peak yourself. So, to get the total energy required, you and a team of friends strap energy meters to your bikes and ride the route in a relay, then add up your individual energy inputs. Researchers are currently using a similar approach, powered by world-class supercomputers, to simulate the energy requirements for candidate drug molecules to permeate cell membranes – shaving weeks of compound testing by determining in advance how readily they’ll enter cells to perform their activity.
Protein ubiquitination is known to result in its proteasomal degradation or to serve as a signal for tissue-specific cellular functions. Here it is reported that mice with a mutant form of the E3 ubiquitin ligase ITCH display reduced litter sizes due to a maternal effect. Mutant females had decreased numbers of implantations, corpa lutea, and extended estrous cycles. The results indicate for the first time that loss of functional ITCH disrupts female reproduction.
Researchers have found one of the oldest and most detailed fossils of the central nervous system yet identified, from a crustacean-like animal that lived more than 500 million years ago. The fossil, from southern China, has been so well preserved that individual nerves are visible, the first time this level of detail has been observed in a fossil of this age.
An international study of almost 120,000 women has newly identified five genetic variants affecting risk of breast cancer, all of which are believed to influence how breast cells respond to the female sex hormone estrogen.
