Cutting back on sleep boosts levels of a chemical signal that can enhance the pleasure of eating snack foods and increase caloric intake, report investigators. It may be part of a mechanism that encourages overeating, leading to weight gain, they say.
In a first-of-its-kind-study, researchers have discovered and applied a new screening technique capable of testing thousands of potential drug compounds to see if those compounds can reverse abnormal DNA unwinding in Ewing sarcoma, a bone and soft tissue cancer that’s most common in teens and young adults.
How do privacy concerns affect how health data is shared? Research explores privacy laws and their effect on health information exchanges in the United States.
Health care providers play an important role in providing accurate information to adolescents about sexual health issues, including prevention of pregnancy and sexually transmitted infections. There has been limited research, however, on how to best provide effective discussions about sexual health with Asian-American adolescents in a culturally sensitive manner.
Women considering abortions are getting medically inaccurate information nearly a third of the time in states that require doctors to provide informed consent materials to their patients, according to a new study.
Today, the gold standard for insulin therapy is the subcutaneous injection of insulin (CSII), despite a non-physiological route of administration with suboptimal glycemic control showed in some patients. Inability of CSII therapy to prevent inflammation and oxidative stress was firstly demonstrated in vivo on treated-diabetic rats, presenting a high variability of glycogen storage associated with glycemic fluctuations. This study suggests that targeting oxidative stress and/or inflammation could help the therapeutic management of diabetic patients.
Currently available animal and human liver models provide limited predictions of human drug efficacy and toxicity, primarily due to metabolic differences and the limited ability of simple 2-D models to recapitulate the complex cellular interactions that lead to toxicity. To fill this gap we have developed a novel 4 cell type, 3-D, microfluidic, human liver model with the ability to monitor multiple cellular toxicity and human disease related functions over at least 28 days.
