Researchers have created a hydrogel scaffold that replicates the environment found within the human breast. The scaffold supports the growth of human mammary tissue from patient-derived cells and can be used to study normal breast development as well as breast cancer initiation and progression.
A cell membrane transporter – CarT – maintains vision in the fruit fly Drosophila by recycling the neurotransmitter histamine in the brain, scientists have discovered.
A tumor’s immune response to a single dose of the HER2 inhibitor trastuzumab predicted which patients with HER2-positive breast cancer would respond to the drug on a more long-term basis, according to the results of a new study.
The brain chemical dopamine regulates how mice learn to avoid a disagreeable encounter. Research has shown that dopamine reinforces ‘rewarding’ behaviors, but to the researchers’ surprise, in a new study they demonstrated that situations that animals learn to avoid are also regulated by dopamine.
Wealthier seniors in Ontario were prescribed a new blood thinner for a common heart rhythm abnormality 1.5 times more often than poorer seniors when the drug was first approved by Health Canada, a new study has found.
Stable environments like constant predator threats, not unstable conditions, generate the non-genetic behavioral changes known as ‘transgenerational response’ in the next generation, researchers have discovered for the first time.
Cutting back on sleep boosts levels of a chemical signal that can enhance the pleasure of eating snack foods and increase caloric intake, report investigators. It may be part of a mechanism that encourages overeating, leading to weight gain, they say.
