Mom's smoking alters fetal DNA

A study of over 6,000 mothers and their newborn children – one of the largest studies of its kind – solidifies the evidence that smoking cigarettes while pregnant chemically modifies a fetus’ DNA, mirroring patterns seen in adult smokers. The researchers also identify new development-related genes affected by smoking. The work suggests a potential explanation for the link between smoking during pregnancy and health complications in children.

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Pharmacy on demand: Portable system can be configured to produce different drugs

Researchers have developed a compact, portable pharmaceutical manufacturing system that can be reconfigured to produce a variety of drugs on demand.

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Born to run? Study suggests love of exercise starts in the womb

Female mice that voluntarily exercise during pregnancy have offspring that are more physically active as adults.

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Scientists discover a missing link between tau and memory loss

Scientists have long known that the protein tau is involved in dementia, but until recently, they did not understand how it hindered cognitive function. In a new study, researchers reveal how tau disrupts a cell’s ability to strengthen connections with other cells, preventing memories from forming.

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3-D 'mini-retinas' grown from mouse and human stem cells

Stem cell science has progressed so that researchers can now share recipes for making human retinas – the part of the eye that is sensitive to light. Researchers now have another efficient way to make 3-D retina organoids, which mimic the organ’s tissue organization, from mouse or human stem cells. Their version of ‘mini-retinas’ offers new perspectives on retina growth, injury, and repair.

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Virus evolution differs by species of mosquito carrier

A new study on how the West Nile virus evolves in four species of mosquitos shows that viruses accumulate mutations in their insect carriers that reduce how well they reproduce when passed on to a bird host. Viruses carried by one of the tropical species were best able to maintain their reproductive fitness and thus spread. The study could help in the prediction of future viral outbreaks.

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Compact drug synthesizer could revolutionize drug delivery

Researchers have developed a system the size of a household fridge that can synthesize a variety of pharmaceuticals in short periods of time, including an antihistamine, an antidepressant, a common local anesthetic, and a central nervous system depressant.

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