Scientists have thought for some time that multiple immunizations, each tailored to specific stages of the immune response, could be used to generate a special class of HIV-fighting antibodies, so-called broadly neutralizing antibodies. New findings provide the first evidence supporting this approach.
A new study expands scientists’ understanding of proteins’ normal functioning. Researchers identified how proteins move and change their shape in order to perform specific jobs. This advancement fills a gap in scientific knowledge that persisted for more than 30 years.
Scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that generate the entire blood system
Over 35 million people worldwide are currently infected by HIV. Antiviral therapies can keep the virus from multiplying. However, no drug can cure infection so far, because various cell types continue to carry the virus in a latent, i.e. quiescent, state. Scientists have now established a model for latent HIV infection of brain cells. The researchers used this model to identify various compounds that affect latency of the virus in the brain.
Highlighting the seismic shift in cancer research and treatment that is underway due to biomarkers and next generation sequencing, a new article offers multiple review articles summarizing the opportunities presented by improvements in molecular testing and analysis.
A blood clot in an abdominal vein may be an indicator of undiagnosed cancer, new research suggests. The study also suggests that these clots predict poorer survival in patients with liver and pancreatic cancer.
By manipulating the activity of Activin receptors in the brain, researchers report that they were able to increase or decrease cocaine-taking and relapse behavior in animal models. The study focused on receptors in regions of the brain involved in pleasure and reward.
