Researchers have developed a highly efficient way to produce chiral multi-centered fused tricyclic compounds of which core structure is often found in bioactive compounds including medicines.
Researchers have identified how some cancer cells are made to move during metastasis. The research provides a better understanding of how cancer spreads and may create new opportunities for cancer drug development.
Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells persisted for more than two years.
For patients with mild cognitive impairment, don’t be surprised if your health care provider prescribes exercise rather than medication. A new guideline for medical practitioners says they should recommend twice-weekly exercise to people with mild cognitive impairment to improve memory and thinking.
New evidence from mice suggests why an antidepressant treatment can alleviate depression in one person but not another.
Resistance to antibiotics poses a serious and sometimes deadly challenge to the treatment of severe bacterial infections. Researchers propose that development of alternative therapies for mild infections could help slow the development and spread of antibiotic resistance.
Uganda is among the countries is sub-Saharan Africa where cholera remains a recurring problem, despite advances in science and technology for prevention, detection and treatment of the infectious disease. Now, researchers have identified cholera hotspots around Uganda to help target interventions.
