Monday, October 31, 2016

New treatment leaves liver cancer cells in limbo

Scientists have shown that a mutation in a gene called Arid1b can cause liver cancer. The gene normally protects against cancer by limiting cell growth, but when mutated it allows cells to grow uncontrollably. The researchers have shown that two existing drugs can halt this growth in human cells. This points to a new approach to treating liver cancer, say researchers.



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Targeting the host to get rid of unwanted guests

A new approach has been developed to combat diseases caused by herpesvirus infections, including everything from cold sores to cancer.



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This new technology could prevent a leading cause of death

Sepsis can kill a person in two days. Normal methods of detecting sepsis take at least that long. But researchers have found a new way to significantly reduce that detection time, giving medical professionals more time to treat the patient.



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Zika infection causes reduced fertility, low testosterone in male mice

Zika targets the male reproductive system, at least in mice, say researchers. Three weeks after Zika infection, male mice had shrunken testicles, low levels of sex hormones and reduced fertility. The results suggest that Zika infection may interfere with men’s ability to have children.



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Making sense of the seneses: 'Context' matters when the brain interprets sounds

The brain’s interpretation of sound is influenced by cues from other senses, explaining more precisely how we interpret what we hear at a particular moment, according to a report.



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New study suggests way to slow skin fibrosis in scleroderma

A possible mechanism behind the fibrosis that occurs in scleroderma has now been identified, a mechanism, researchers say, that may one day lead to a treatment for the disease.



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Acupuncture lowers hypertension by activating opioids, study finds

Regular electroacupunture treatment can lower hypertension by increasing the release of a kind of opioid in the brainstem region that controls blood pressure, investigators have found.



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First-in-human of new polymer-free stent demonstrates favorable angiographic, imaging-based outcomes at nine-months

A first-in-human study of a new polymer-free drug-filled stent, which provides controlled drug elution from an internal lumen, indicated non-inferior in-stent late lumen loss at nine-months compared with historical zotarolimus-eluting stent (Resolute) data. In addition, there was no binary restenosis, and a high degree of early stent strut coverage with minimal malapposition.



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Social media proves effective as a tool for antimicrobial stewardship

A new study examines the use of social media platforms to inform young physicians about proper use of antimicrobial agents such as antibiotics. Currently, as much as 50 percent of all antibiotic use is inappropriate, leading to such unintended consequences such as antibiotic toxicity and increased antimicrobial resistance. Ensuring optimal use of antibiotics continues to be a central public health concern, and medical residents are a central focus of efforts to improve education in this field. But the question remains as to the best way to reach them.



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Artificial muscles show more flex

Artificial muscles made significant gains when a literal twist in the development approach uncovered the tensile or stretchy abilities of polymer fibers once they were twisted and coiled into a spring-like geometry. In a similar manner to the powerful climbing tendrils of cucumber plants, the unique geometry gives the coil a flexing motion when fiber material shrinks a reaction that can be controlled with heat. Now, researchers have improved these tensile properties even further by focusing on the thermal properties of the polymer fiber and the molecular structure that makes best use of the chiral configuration.



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