Monday, February 29, 2016

'Informed consent' states often give women considering abortions inaccurate information

Women considering abortions are getting medically inaccurate information nearly a third of the time in states that require doctors to provide informed consent materials to their patients, according to a new study.



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Diabetic management: Subcutaneous insulin therapy fails to protect against oxidative stress and inflammation

Today, the gold standard for insulin therapy is the subcutaneous injection of insulin (CSII), despite a non-physiological route of administration with suboptimal glycemic control showed in some patients. Inability of CSII therapy to prevent inflammation and oxidative stress was firstly demonstrated in vivo on treated-diabetic rats, presenting a high variability of glycogen storage associated with glycemic fluctuations. This study suggests that targeting oxidative stress and/or inflammation could help the therapeutic management of diabetic patients.



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A human liver microphysiology platform for studying physiology, drug safety, and disease

Currently available animal and human liver models provide limited predictions of human drug efficacy and toxicity, primarily due to metabolic differences and the limited ability of simple 2-D models to recapitulate the complex cellular interactions that lead to toxicity. To fill this gap we have developed a novel 4 cell type, 3-D, microfluidic, human liver model with the ability to monitor multiple cellular toxicity and human disease related functions over at least 28 days.



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A new way to discover DNA modifications

DNA is made from four nucleosides, each known by its own letter – A, G, C, and T. However, since the structure of DNA was deciphered in 1953, scientists have discovered several other variants that are often added to the DNA sequences to replace one of the usual four letters.



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Online courses: MOOC instructors may need more support for successful courses

Supporting instructors of massive open online courses – MOOCs – may be just as important to the creation of long-term, successful courses as attracting and supporting students, according to a group of researchers.



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Cancer patients with limited finances are more likely to have increased symptoms and poorer quality of life

If you’re a lung or colorectal cancer patient, what’s in your wallet could determine your level of suffering and quality of life during treatment, according to a new study.



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Two-way clustering method for QSAR modeling of diverse set of chemicals

New articles developed in silico models for the estimation of potential mutagenicity of chemicals from their structure without the input of any other experimental data.



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Does daylight saving time increase risk of stroke?

Turning the clock ahead or back one hour during daylight saving time transitions may be tied to an increased risk of ischemic stroke, but only temporarily, according to a preliminary study.



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Less than half of pediatricians inquire about maternal mental health

Although asking about maternal depression increased among pediatricians by about 30 percent between 2004 and 2013, less than half of pediatricians usually screen for the condition.



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Study points to cannabis' effect on emotion processing

According to researchers, cannabis significantly affects users’ ability to recognize, process and empathize with human emotions like happiness, sadness and anger.



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