A combination of proteins that could improve clinical bone restoration, and could lead towards the development of therapeutic treatments for skeletal defects, bone loss and osteoporosis, report researchers. They found that the combination of two proteins, NELL-1 and BMP2, increased bone formation while inhibiting the formation of fat cells. By contrast, NELL-1 encourages stem cells to form bone cells instead of fat cells. Used together, the proteins stimulate bone production more than either does alone.
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