How the insulin receptor works

As we are approaching the 100th anniversary of the discovery of insulin, a wide array of its signaling pathways has been defined. However, the initial step in insulin action, i.e. the engagement with its cell-surface receptor and the resulting conformational change, which propagates across the plasma membrane to the intracellular module, remains poorly understood.

from Top Health News – ScienceDaily http://bit.ly/2sHFj3k
from Tumblr http://bit.ly/2ob8N55