Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical utility is limited by its tendency to produce unintended genetic errors. Researchers centered at Osaka University developed a modified CRISPR-Cas9 system that uses single-stranded nicking, rather than DNA cleavage, to generate highly precise changes to a target gene. The technique offers a more accurate and safer editing strategy for future gene therapy applications.
from Top Health News – ScienceDaily http://bit.ly/2nOHa0X
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