Seeing cell to cell differences for first time explains symptoms of rare genetic disorders

Every cell in the body has two genomes, one from the mother and one from the father. Until now, researchers have lacked the tools to examine – in a single cell -the exact readout from each genome to make RNA. Using a new technology that allows researchers to do just that, an interdisciplinary team examined a rare disease in which these two genomes are expressed differently throughout the body, even sometimes in the same organ.

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