Researchers developed an in vivo mutation prevention method that enables the DNA-cleaving Cas9 enzyme to discriminate between genomic target sites differing by a single nucleotide and to exclusively cut the unwanted one. In proof-of-concept studies performed in bacterial E. coli strains grown in culture or the mouse gastrointestinal tract, the approach can prevent the survival of antibiotic resistant variants.
from Top Health News – ScienceDaily http://bit.ly/2I5kuls
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